Victor de Lorenzo, member of the advisory board of OMIC-Engine, was invited by Dr G. Skretas member of the research infrastructure to give a talk on his pioneering work on the implementation of synthetic biological approaches to environmental clean-up. Dr de Lorenzo gave a fascinating overview on the development of a range of synthetic biology tools utilized on chassi microorganisms Pseudomonas putida KT2440 and the implementation of these tools towards the development of novel engineered strains and consortia of engineered bacteria, attached to carriers, able to carry out removal of toxic organic pollutants in an optimized mode and attain full conversion of the toxicants.